Journal Title：Computational Biology And Chemistry

Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered.

Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.

Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.

Computational Biology and Chemistry 发表计算生命科学所有领域的原创研究论文和评论文章。在核酸和蛋白质序列研究、分子进化、分子遗传学（功能基因组学和蛋白质组学）、生物学特异性或化学生物学特异性建模的理论和实践以及结构核酸和蛋白质的生物学特别受欢迎。还将考虑在生物信息学、系统生物学、生态学、计算药理学、新陈代谢、生物医学工程、流行病学和统计遗传学方面的高质量研究工作。

鉴于其固有的不确定性，应彻底验证蛋白质建模和分子对接研究。在没有验证实验结果的情况下，例如，分子动力学模拟的使用以及详细的自由能计算应该用作支持主要结论的补充技术。不考虑提交没有额外生物学见解的过早建模练习。

审稿文章一般由编辑委托，未经明确邀请不得提交给期刊。但是，欢迎潜在作者发送简短（一到三页）的概要，由编辑进行评估。