Journal Title:Frontiers In Molecular Neuroscience
Frontiers in Molecular Neuroscience is a first-tier electronic journal devoted to identifying key molecules, as well as their functions and interactions, that underlie the structure, design and function of the brain across all levels. The scope of our journal encompasses synaptic and cellular proteins, coding and non-coding RNA, and molecular mechanisms regulating cellular and dendritic RNA translation. In recent years, a plethora of new cellular and synaptic players have been identified from reduced systems, such as neuronal cultures, but the relevance of these molecules in terms of cellular and synaptic function and plasticity in the living brain and its circuits has not been validated. The effects of spine growth and density observed using gene products identified from in vitro work are frequently not reproduced in vivo. Our journal is particularly interested in studies on genetically engineered model organisms (C. elegans, Drosophila, mouse), in which alterations in key molecules underlying cellular and synaptic function and plasticity produce defined anatomical, physiological and behavioral changes. In the mouse, genetic alterations limited to particular neural circuits (olfactory bulb, motor cortex, cortical layers, hippocampal subfields, cerebellum), preferably regulated in time and on demand, are of special interest, as they sidestep potential compensatory developmental effects.
Frontiers in Molecular Neuroscience 是一本一流的电子期刊,致力于识别关键分子及其功能和相互作用,这些分子是大脑各个层面的结构、设计和功能的基础。我们期刊的范围包括突触和细胞蛋白、编码和非编码 RNA,以及调节细胞和树突状 RNA 翻译的分子机制。近年来,已经从减少的系统(例如神经元培养物)中鉴定出大量新的细胞和突触参与者,但这些分子在活体大脑及其电路中的细胞和突触功能以及可塑性方面的相关性尚未得到验证.使用从体外工作中鉴定的基因产物观察到的脊柱生长和密度的影响通常不会在体内重现。我们的期刊对基因工程模式生物(秀丽隐杆线虫、果蝇、小鼠)的研究特别感兴趣,其中细胞和突触功能和可塑性的关键分子的改变会产生明确的解剖学、生理学和行为学变化。在小鼠中,遗传改变仅限于特定的神经回路(嗅球、运动皮层、皮质层、海马亚区、小脑),最好是及时和按需调节,因为它们避开了潜在的代偿性发育影响。
大类学科 | 小类学科 | 分区 | Top期刊 | 综述期刊 |
医学 | NEUROSCIENCES 神经科学 | 2区 | 是 | 是 |
大类学科 | 小类学科 | 分区 |
医学 | NEUROSCIENCES 神经科学 | 2区 |
期刊名称 | 领域 | 中科院分区 | 影响因子 |
Language Speech And Hearing Services In Schools | 医学 | 2区 | 2.400 |
International Journal Of Bipolar Disorders | 医学 | 2区 | 4.000 |
International Journal Of Bipolar Disorders | 医学 | 2区 | 4.000 |
Seminars In Nuclear Medicine | 医学 | 2区 | 4.900 |
Current Allergy And Asthma Reports | 医学 | 2区 | 5.500 |
Current Obesity Reports | 医学 | 2区 | 8.800 |