Journal Title：Biopharmaceutics & Drug Disposition

Biopharmaceutics & Drug Dispositionpublishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs. These includes:

- animal and human pharmacological studies that focus on therapeutic response. pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites,

- in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in man

- studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition,

- simulation and modeling in drug discovery and development

- theoretical treatises

- includes themed issues and reviews

and exclude manuscripts on

- bioavailability studies reporting only on simple PK parameters such as Cmax, tmax and t1/2 without mechanistic interpretation

- analytical methods

Biopharmaceutics & Drug Disposition 发表有关生物药剂学、药物处置、药代动力学和药效学的原创评论文章、简短交流和报告，尤其是那些与药物发现/开发和药物治疗用途直接相关的文章。其中包括：

- 专注于治疗反应的动物和人类药理学研究。药物及其代谢物的血浆和组织浓度相关的药效学和毒性，

- 体外和体内药物吸收、分布、代谢、转运和排泄研究，促进与人体药物使用相关的研究

- 膜转运和酶的研究，包括它们的调控以及药物基因组学对药物吸收和处置的影响，

- 药物发现和开发中的模拟和建模

- 理论论文

- 包括主题问题和评论

并排除手稿

- 仅报告简单 PK 参数（如 Cmax、tmax 和 t1/2）的生物利用度研究，没有机械解释

- 分析方法